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Saturday, May 6, 2023

Revolutionizing Mental Health and Well-Being with Wearable Watches: The Future of Personalized Health Monitoring

Wearable devices such as smartwatches and fitness trackers have become popular tools for monitoring physical activity, heart rate, sleep quality, and more. But, researchers from the University of Cambridge have developed a new AI-powered system that can analyse the voice and facial expressions of a person wearing a smartwatch or smart glasses. The system, called EmoWatch, uses deep learning algorithms to recognise the emotional state of the user based on subtle cues such as tone of voice, pitch, volume, speech rate, facial expressions, and eye movements. EmoWatch can accurately identify six basic emotions: happiness, sadness, anger, fear, disgust, and surprise. The system can also infer the user’s stress level, mood, and personality traits.

EmoWatch could have various applications for improving the mental health and well-being of users. For example, the system could provide personalised feedback and suggestions to help users cope with stress, anxiety or depression. The system could also alert users to potential mental health issues or risks, such as burnout or suicidal thoughts. Additionally, the system could enable users to share their emotional state with their friends, family, or therapists, and receive social support and empathy.

The accuracy of machine learning models used to gauge mental well-being from wearables data is still being researched. However, researchers from the Icahn School of Medicine at Mount Sinai in New York applied machine learning models to the data passively collected by wearables like the Apple Watch to gauge a person’s resilience and mental well-being. They found that the models were able to predict mental health outcomes with an accuracy of up to 90%.

To use these models to improve mental health, machine-learning algorithms may be able to make sense of the wearable data, mapping them onto the individual’s past experiences and the experiences of other users. The technology may then be able to encourage the individual to engage in certain behaviors that have improved their well-being in the past, or to reach out to their physician. Additionally, ML algorithms could aid mental health providers in determining whether patients are at high risk of acquiring a specific mental health illness by identifying crucial behavioral biomarkers. The algorithms may also aid in the monitoring of a treatment plan’s effectiveness.

However, there are some ethical and privacy challenges associated with EmoWatch and using wearables to monitor mental health. It is crucial to ensure that the user's data is secure and confidential, and that the user has control over who can access their emotional information.

It's important to note that EmoWatch is not intended to replace human interaction or professional diagnosis, but rather to complement and enhance them. The researchers plan to conduct further studies to evaluate the performance and usability of EmoWatch in different scenarios and contexts. They also hope to expand the system’s capabilities to recognise more complex and nuanced emotions, such as boredom, frustration or sarcasm. Ultimately, they aim to create a wearable device that can understand and support the user’s mental health and well-being in a natural and unobtrusive way.

Numerous wearables, such as Oura Ring, Apollo Wearable, Apple Watch Series 8, Bellabeat Ivy, Muse Headband, and Garmin Smartwatch, aid in monitoring mental health. These devices use different technologies to manage stress and anxiety symptoms, benefiting the users and mental healthcare system. Experts anticipate that wearables will decrease mental healthcare expenses for patients and the system.

In conclusion, AI-powered wearables have the potential to revolutionize the way we monitor and manage our mental health and well-being. The EmoWatch system developed by researchers from the University of Cambridge, and the machine learning models used by researchers from the Icahn School of Medicine at Mount Sinai, are just two examples of how this technology can be applied. However, there are still ethical and privacy concerns that need to be addressed, as well as ongoing research into the accuracy and limitations of these models.

Despite these challenges, the possibilities are promising. Wearable devices that can understand and support the user's mental health and well-being in a natural and unobtrusive way could help millions of people around the world lead happier, healthier lives. As this technology continues to evolve and improve, it will be interesting to see how it will be integrated into our daily lives and how it will transform the field of mental health.

Google's Foldable Phone, 2023: All You Need to Know About the Pixel Fold

Google's First Foldable Phone: Pixel Fold Confirmed

After months of speculation and rumors, Google has finally confirmed the existence of its first foldable phone, the Pixel Fold. As anticipated, the tech giant owned by Alphabet has unveiled a teaser clip of the device, and it closely resembles the design that has been circulating in rumors and images for the past few months.

The Pixel Fold boasts a book-like design that is reminiscent of the Samsung Galaxy Fold series and the recently launched Tecno Phantom V 5G.

The highly anticipated Google Pixel Fold is set to be launched on May 10 at the Google I/O event. A "Notify Me" button is available on a landing page on the Google Store in the US, allowing users to stay updated about the upcoming foldable phone. While Google has not yet revealed the markets where the device will be released, it is unclear whether the Pixel Fold will be available in India.

The price and availability of the Pixel Fold are still unknown, but some analysts estimate that it could cost between $1,400 and $1,800. Google's teaser page for the phone only says that it is "coming soon". The Pixel Fold will join Google's existing lineup of smartphones, which includes the Pixel 6a, Pixel 7, and Pixel 7 Pro.

However, according to market experts with access to inside information, this premium device is set to launch soon at Google's developers' conference, Google I/O 2023. The event is scheduled for May 10, and the Pixel Fold is speculated to launch in the Indian markets sometime this year with a rumored price tag of ₹145,000. This is yet to be confirmed, and eager buyers will have to hold onto their excitement and wait patiently until the launch date.

Design and Display

The Pixel Fold sports an inward-folding design, a polished metal frame, protective glass on the cover and rear, and a fingerprint reader on the side. On the cover screen, it has a top-centered punch-hole cut-out. The selfie camera on the inner display is mounted on the top bezel.

The device features a 7.6-inch QHD+ (1840x2208 pixels) OLED main panel with a 120Hz maximum refresh rate, 308ppi pixel density, and a 6:5 aspect ratio for a tablet-like on-screen experience.

Camera and Processor

The exact configuration and specifications of the rear camera bump are unknown. However, some reports suggest that the phone could have a 50-megapixel main camera along with two 12-megapixel cameras and an 8-megapixel one.

The Pixel Fold is supposedly powered by the Google Tensor G2 processor, which is the second-generation smartphone processor designed for the Pixel range. It has 2 cores Cortex-X1 at 2850 MHz, 2 cores Cortex-A78 at 2350 MHz, and 4 cores Cortex-A55 at 1800 MHz. It might also include 256/512GB of UFS 3.1 storage and 12GB of LPDDR5 RAM. The device is said to feature the most robust hinge of any foldable phone.

Software and Features

The Pixel Fold will run on Android 12, which is expected to be unveiled at Google I/O. The software will probably have some optimizations and features for the foldable form factor, such as adaptive widgets and user interface elements. The phone could also support some of Google’s signature features, such as Assistant, Photos, Lens, and Call Screen.

Release and Competition

The Pixel Fold is Google’s attempt to enter the foldable phone market, which is still niche but growing rapidly. According to Counterpoint Research, foldable phone shipments increased by 454% year-on-year in the first quarter of 2021, reaching 2.8 million units. Samsung dominates this segment with a 74% market share, followed by Huawei with 8% and Motorola with 7%.

The Pixel Fold could offer some advantages over its rivals, such as a smoother software experience, faster updates, better camera performance, and tighter integration with Google’s services and ecosystem. However, it will also face some challenges, such as high price, durability issues, battery life concerns, and limited app compatibility.

Exciting New Product

The Pixel Fold is one of the most anticipated devices of 2023. With its impressive features, the Pixel Fold is expected to make a splash in the foldable phone market. Stay tuned for more updates and coverage on this exciting new product.

The Pixel Fold is one of the most highly anticipated devices of 2023, as it represents Google's entry into the foldable smartphone market, which is rapidly growing. The device is expected to offer some advantages over its competitors, such as a smoother software experience, faster updates, better camera performance, and tighter integration with Google's services and ecosystem.

However, the Pixel Fold will also face some challenges, such as high price, durability issues, battery life concerns, and limited app compatibility. Nevertheless, with the promise of a robust hinge, powerful processor, and impressive display, the Pixel Fold is poised to make a significant impact in the foldable smartphone space.

With the launch of the Pixel Fold at Google I/O 2023 just around the corner, there is much excitement and anticipation among tech enthusiasts and consumers alike. It remains to be seen how the Pixel Fold will be received in the market, but one thing is for sure: Google has once again set its sights on pushing the boundaries of what is possible with mobile technology.

Friday, May 5, 2023

A Guide to Monkeypox: Symptoms, Treatment, and Prevention Strategies

Researchers from the London School of Hygiene and Tropical Medicine (LSHTM) and Public Health England (PHE) have launched a study to better understand the behavior and spread of the monkeypox virus.

Monkeypox is a rare but potentially fatal viral infection that causes a blistering rash and fever. It is primarily found in Central and West Africa, where it is transmitted by contact with infected animals or humans, but there have been several cases reported in other parts of the world, including the UK.

The study, funded by the Wellcome Trust, aims to analyze the genetic sequences of the monkeypox virus collected from patients in different countries and regions. By comparing the genetic variations of the virus, the researchers hope to trace its origins and evolution, as well as identify any factors that may influence its transmission and severity. This could help improve the diagnosis, prevention, and treatment of monkeypox, as well as inform public health policies and responses.

The researchers plan to identify the sources and routes of transmission of the virus, as well as its genetic diversity and evolution. This information will help to improve the surveillance and control of monkeypox outbreaks and inform the development of new diagnostic tools and vaccines.

Dr. Simon Cauchemez, the lead investigator of the study, said that monkeypox is a serious and emerging threat to global health, and that understanding how it behaves and evolves in different settings and populations is necessary to develop effective strategies to control it. Dr. Meera Chand, a consultant microbiologist at PHE and a co-investigator of the study, said that monkeypox is a rare but potentially life-threatening infection that can be transmitted from person to person. The study will help to enhance surveillance and response capabilities for monkeypox and other emerging infections.

The study is part of a larger project on emerging zoonotic diseases in Africa and involves collaboration with researchers from Nigeria, Cameroon, Sierra Leone, and the Democratic Republic of Congo. It is funded by the UK Research and Innovation (UKRI) Global Challenges Research Fund (GCRF).

A case of monkeypox was diagnosed in Sydney, the first case found in NSW since November last year. Gay, bisexual, and other men who have sex with men are urged to be on the lookout for symptoms and to get vaccinated if they haven’t already, according to Dr. Vicky Sheppeard, director of the South Eastern Sydney Public Health Unit.

To summarize, monkeypox is a rare disease caused by a virus that is similar to the smallpox virus. Its symptoms include fever, headache, muscle aches, backache, lymphadenopathy (swollen lymph nodes), and a general feeling of malaise, followed by a rash that develops on the face and spreads to the trunk and limbs. The disease can be severe in some cases, but the treatment is mainly supportive and involves managing the symptoms.

Currently, there is no specific antiviral treatment for monkeypox, but research is ongoing into the development of a vaccine. Prevention measures include avoiding contact with wild animals, practicing good hygiene, and avoiding close contact with individuals who are suspected to have the disease.

It is important to raise awareness of the disease, particularly among those who live in or travel to areas where the virus is prevalent, to prevent the spread of the disease and ensure early diagnosis and treatment for those affected.

How to Protect Yourself from Monkeypox: Symptoms, Treatment, and Prevention

Guardians of the Galaxy: Volume III - A Cosmic Adventure of Redemption and Reunions

Guardians of the Galaxy: Volume III - A Marvel-ous Space Epic!

Guardians of the Galaxy Vol. 3 is a 2023 American superhero film based on the Marvel Comics superhero team Guardians of the Galaxy, produced by Marvel Studios and distributed by Walt Disney Studios Motion Pictures1. The movie is directed by James Gunn.



Guardians of the Galaxy Vol. 3 is the third and final journey in the Guardians of the Galaxy, comedy adventure film series, which is part of the greater Marvel Cinematic Universe (MCU). Here are some details about the movie:
- Director: James Gunn
- Writer: James Gunn
- Release date: 5th May 2023
- Cast: Chris Pratt as Peter Quill/Star-Lord, Zoe Saldana as Gamora, Dave Bautista as Drax the Destroyer, Vin Diesel as Groot (voice), Bradley Cooper as Rocket Raccoon (voice), Karen Gillan as Nebula, Pom Klementieff as Mantis, and Sean Gunn as Kraglin.

According to James Gunn the movie addresses the origins of Rocket Raccoon, the group's resident genetically-modified raccoon, and delves into the backstory of some of the other characters as well. Gunn has also described the movie as the "epic conclusion" in the last phase to the story he started with the first two Guardians of the Galaxy films.

The story of the film (The plot)

Have you heard of the Guardians of the Galaxy? Well, they're a group of heroes who protect the galaxy from bad guys. One day, they set up their headquarters on a place called Knowhere when suddenly they were attacked to get revenge on the Guardians by Adam, a superpowered being created by the Sovereign's empress, Ayesha, for revenge for stealing from her.

In the attack, Rocket, the raccoon, got hurt badly. The problem was, he had a "kill switch" inside him, which meant the Guardians couldn't help him unless they could find an override code.

So the team had to go on a mission to Orgocorp's headquarters to retrieve the override code and try to find a way to save Rocket.

They thought they could find it at the headquarters of a guy named the High Evolutionary, who created Rocket.

The High Evolutionary, though, wanted Rocket back really bad, so he became obsessed with finding him.

The Guardians had to sneak into his headquarters. With the help of some friends called the Ravagers and a girl named Gamora who was part of the Guardians, they managed to sneak into Orgocorp and get Rocket's file, but they were attacked by the guards and had to escape quickly.

They figured out that a scientist named Theel might have the code in his memory, so they went looking for him. But Gamora, who was really mad at the team for always making separate plans and Peter Quill for trying to make her into someone she wasn't, decided to leave.

While they were on their mission, Ayesha and Adam found out where they were and followed them. They also went to a planet called Counter-Earth.

Peter, Groot, and another girl named Nebula managed to find Theel, but they were captured by the High Evolutionary's ship. Meanwhile, Gamora and another Guardian named Drax stayed behind with Rocket.

Adam attacked Gamora, but she was able to defeat him and rescue Rocket. Meanwhile, Peter, Groot, and Nebula managed to get away from the ship and get the code from Theel's memory.

There were also some animals that were being experimented on by the High Evolutionary, and Rocket wanted to rescue them. But the High Evolutionary attacked him and he almost didn't make it. However, the Guardians were able to defeat the High Evolutionary and save the animals.

After all that, the Guardians decided to go their separate ways. But in a mid-credits scene, we see that there's a new team of Guardians, led by Rocket. And in a post-credits scene, we see Peter reuniting with his grandfather.

Guardians of the Galaxy Vol. 3 had its world premiere at Disneyland Paris on April 22, 2023, and was released in the United States on May 5, 2023.

Here is the release info

Get the overview, gallery and posters

Trailer in Hindi

Action-Packed Thriller 'Operation Fortune: Ruse de Guerre' Now Available for Streaming on OTT Lionsgate Play in India

Spy Thriller: Chasing 'The Handle'- A High-Stakes Adventure of Espionage and Intrigue





Operation Fortune: Ruse de Guerre is a 2023 spy action comedy film directed by Guy Ritchie and written by Ritchie, Ivan Atkinson, and Marn Davies.

The film stars Jason Statham, Aubrey Plaza, Josh Hartnett, Cary Elwes, Bugzy Malone and Hugh Grant1. The plot revolves around a spy named Orson Fortune (Statham), who must retrieve a stolen high-tech device before an arms dealer (Grant) can sell it to the highest bidder.

A gang of Ukrainian mobsters manage to steal a device known as “The Handle” from a secret facility in the United States. The device is capable of hacking into any computer system in the world. Orson Fortune (Jason Statham) is tasked with retrieving the device before it falls into the wrong hands. He assembles a team of operatives and recruits one of Hollywood’s biggest movie stars to help them on an undercover mission when the sale of a deadly new weapons technology threatens to disrupt the world order.

The plot:

So, there's this device called "The Handle" that's worth billions of dollars and a group of Ukrainian mobsters stole it. The British government hires Nathan Jasmine to get it back before arms dealer Greg Simmonds sells it to the highest bidder.

The team tracks down the courier carrying the device to Madrid, but their search is disrupted by Nathan's rival, Mike. However, Sarah, a skilled hacker on the team, manages to copy the contents of the device.

The team learns that Simmonds, an arms dealer, is planning to sell the device to two bio-tech moguls who intend to cause a worldwide financial collapse. To stop this, the team plans to infiltrate a charity gala hosted by Simmonds in Cannes, where they blackmail his favorite movie star to help distract him. The team then heads to Turkey to exchange the device, but things take a turn when Mike and his men interfere and steal the device.

Fortunately, Simmonds is still willing to help the team, as he lost his commission due to Mike's actions. Simmonds tells the team that the buyers of the device are the bio-tech moguls, Trent and Arnold. Orson and JJ, another member of the team, clear heavy security on the ground level, while Simmonds and Danny, the movie star, head up to the tower to confront Mike and the moguls. Simmonds demonstrates his ability to cause harm to their loved ones if he isn't paid for the device, and he and Danny manage to leave before the situation becomes violent.

Orson arrives just in time to take out Mike and retrieve the device. In the end, the team decides to go on vacation, and Orson uses the proceeds from a robbery at the Ukrainians' villa to finance Danny's new film about the events, with Simmonds acting as an on-set producer.

The movie was theatrically released in international territories on January 4, 2023, and theatrically released in the United States on March 3. It was released digitally on Amazon Prime Video in the United Kingdom on April 7.

Ruse de Guerre can be watched online on Lionsgate Play in India, May 5 onwards.

The spy adventure made USD37.6 million at the box office worldwide. It remains to be seen how it fares on OTT.

Everything You Need to Know About 'Operation Fortune: Ruse de Guerre' OTT Release: Cast, Plot, and Where to Watch

Thursday, May 4, 2023

Air Pollution and Heart Health: How Pollutants Increase the Risk of Arrhythmia, Stroke, and Heart Attack

Air pollution has been linked to various health problems, including heart disease. The fine particulate matter present in polluted air can cause inflammation throughout the body, including the blood vessels. These particles can enter the bloodstream and travel to the heart, where they can cause damage and contribute to the development of heart disease.

According to Times of India, air pollution can cause restricted blood flow to the heart and other major blood vessels increasing the chances of cardiovascular events like heart attack and stroke. Experts say that the tiny particles can cause narrowing of the heart arteries which leads to heart stoppage in the blood flow and thus causes a heart attack.

The particulate matter from pollutants that we inhale can cause inflammation in our lungs and cardiovascular system. This inflammation can lead to atherosclerosis, a condition where plaque builds up in arteries, narrowing them and forcing the heart to work harder, leading to an increased heart rate. This increase in heart rate can put a strain on the heart and increase the risk of heart attack or stroke. Moreover, air pollution can cause irregular heartbeats or arrhythmias by disrupting the electrical impulses that regulate our heartbeat.

​ Additionally, air pollution can lead to an increase in blood pressure and the formation of blood clots, both of which can increase the risk of heart attacks and strokes. Exposure to air pollution over an extended period can also lead to the thickening of the left ventricle in the heart, which is a sign of heart dysfunction.

According to Johns Hopkins Medicine, a heart attack occurs when an artery that sends blood and oxygen to the heart is blocked. Fatty, cholesterol-containing deposits build up over time, forming plaques in the heart’s arteries. If a plaque ruptures, a blood clot can form. The clot can block arteries, causing a heart attack. The article also explains the symptoms of a heart attack and what to do if you think you are having one.

According to Better Health Channel, heart disease and stroke are part of a group of cardiovascular diseases that affect your heart and blood vessels. Stroke is a condition in which the brain can’t get blood flow. This happens because one or more blood vessels leading to the brain is blocked or bursts. Heart disease may also be a direct cause of stroke. About one in four cerebral infarctions are due to embolism from the heart to the brain, mainly because of atrial fibrillation, but also because of diseases such as acute myocardial infarction, dilated cardiomyopathy and prosthetic heart valves (cardioembolic stroke).

​ Overall, air pollution can have a significant impact on cardiovascular health, and it is important to take steps to reduce exposure, such as using air purifiers and avoiding areas of high pollution when possible.

Effects of Air Pollution on the Heart's Electrical System and Risk of Arrhythmia

Air pollution has been linked to an increased risk of cardiovascular disease, including arrhythmia. Studies have found that exposure to air pollutants such as nitrogen dioxide, sulfur dioxide, carbon monoxide, ozone, and particulate matter can disrupt the normal functioning of the heart's electrical system, leading to abnormal heart rhythms. Specifically, exposure to fine particles and coarse particles in the air has been associated with a higher risk of atrial fibrillation, supraventricular tachycardia, and premature heartbeats. These findings highlight the urgent need to reduce air pollution levels and promote clean air policies to protect public health and prevent cardiovascular disease.

No wonder the scientists the world over are worried about the growing menace of air pollution which today poses before them a greater global health challenge that affects millions of people worldwide every year.

According to South Florida Cardiovascular Associates, air pollution can lead to the blocking and narrowing of blood vessels, causing increased blood pressure. It can damage blood vessels, increase the risk of blood clotting and cause abnormal heartbeat. The article also states that air pollution can cause plaque in a person’s blood vessel to rupture, which can lead to heart attack and stroke.

Vulnerable populations such as the elderly, people with pre-existing heart conditions, and those living in areas with high levels of pollution are at a higher risk of developing cardiovascular diseases. The World Health Organization estimates that air pollution contributes to 7 million premature deaths each year, and cardiovascular disease is one of the leading causes.

To protect ourselves from the harmful effects of air pollution, we must take steps to reduce our exposure. This includes avoiding outdoor activities during times of high pollution, using air filters in our homes, and transitioning towards cleaner forms of transportation. Governments and policymakers must also take action to regulate industrial emissions and promote cleaner air policies.

According to a report by Euronews Next, a new study has found that exposure to air pollution has been linked to an increased risk of irregular heartbeat, in a large study of 322 Chinese cities. Two common irregular heartbeat conditions - known as arrhythmia - are atrial fibrillation and atrial flutter, both of which can progress to more serious heart disease1. The study found that acute exposure to ambient air pollution was associated with increased risk of symptomatic arrhythmia. The risks occurred during the first several hours after exposure and could persist for 24 hours.

According to a report by Time, a new study in the Canadian Medical Association Journal has closely tied air pollution linked to the burning of fossil fuels, especially coal, to another heart risk: arrhythmia, or irregular changes in heartbeat1. The study found that acute exposure to air pollution was associated with increased risk of symptomatic arrhythmia. The risks occurred during the first several hours after exposure and could persist for 24 hours

According to The Week, long-term exposure to air pollution has been associated with an increased risk of arrhythmia, or irregular heartbeat. The study evaluated hourly exposure to air pollution and the sudden onset of arrhythmia symptoms using data from 2025 hospitals. The research found that the risk of arrhythmia increased by 1.2% for every 10 micrograms per cubic meter increase in PM2.5.

PM2.5 is a fine particulate matter that is less than 2.5 micrometers in diameter and is considered one of the most harmful air pollutants. It can penetrate deep into the lungs and enter the bloodstream, causing inflammation and oxidative stress.

“We found that acute exposure to ambient air pollution was associated with increased risk of symptomatic arrhythmia,” said Dr. Renjie Chen, of Fudan University in Shanghai, one of the paper’s 20 co-authors, in a statement. “The risks occurred during the first several hours after exposure and could persist for 24 hours.” source:Air Pollution Affects Heartbeat

Dr. Renjie Chen and his colleagues collected data from 2,025 hospitals in 322 cities in China between 2015 and 2021. The data included 190,115 patients who went to emergency rooms complaining of arrhythmia. The researchers cross-referenced those reports with records from air quality monitoring stations located within 50 km (31 miles) of each hospital on the day each patient appeared. The average range for each monitoring station was actually much closer—just 4.4 km (2.7 miles) from each hospital.

According to Time, the scientists analyzed four distinct types of arrhythmia, namely atrial fibrillation, atrial flutter, premature heartbeats, and supraventricular tachycardia. The study concentrated on six hazardous pollutants monitored by air quality stations, namely nitrogen dioxide, sulfur dioxide, carbon monoxide, ozone, coarse particles measuring 2.5 to 10 micrometers, and fine particles smaller than 2.5 micrometers. Among the 190,115 individuals in the study, atrial fibrillation was the most common arrhythmia, affecting 50.6% of the participants, followed by supraventricular tachycardia at 24.8%, premature beats at 21.9%, and atrial flutter at 2.8%. However, the pollutants did not affect all the conditions equally, as atrial flutter and supraventricular tachycardia were more closely associated with unclean atmospheric conditions.

The findings of this study reinforce the detrimental effects of air pollution on cardiovascular health. The strong association between arrhythmias and exposure to pollutants highlights the urgent need to reduce harmful emissions and promote cleaner air policies. Protecting vulnerable populations, including the elderly and those with pre-existing heart conditions, should be a top priority for governments and policymakers worldwide. By taking decisive action to address air pollution, we can help prevent millions of premature deaths caused by cardiovascular disease each year and create a healthier and safer environment for all.

Wednesday, May 3, 2023

Are Beta Blockers Effective in Preventing Heart Attacks? Here's What Recent Studies Say

It is quite common for doctors these days to prescribe beta-blockers to patients who have a weak heart with high blood pressure or have recently suffered a heart attack. Let us try to unravel how effective beta-blockers are in preventing heart attacks.

It's important to note that beta-blockers are no longer the go-to option for reducing blood pressure. While they may still be prescribed for heart disease patients, there are potentially more effective alternatives available for those with high blood pressure. That said, beta-blockers remain a popular treatment option for angina, as they can decrease the heart rate, lower the heart's oxygen demand, and reduce the frequency of angina attacks.

Beta-blockers are a class of medicines that block the effects of hormones like adrenaline on beta receptors, which are found on cells of the heart, blood vessels, lungs, and other organs. By blocking these receptors, beta-blockers slow down the heart rate, relax the blood vessels, lower the blood pressure, and help the heart beat more regularly. There are different types of beta receptors, and some beta-blockers are selective for one type over another.

Beta-blockers work mainly by slowing down the heart. They do this by blocking the action of hormones like adrenaline. Beta-blockers prevent adrenaline, a stress-related hormone, from making contact with your heart's beta receptors. This prevents adrenaline from making your heart pump harder or faster.

Beta-blockers are available in different formulas with different routes of administration, including oral, intravenous, and ophthalmic. Beta-blockers are usually taken once or twice a day with meals and should generally be taken at the same time every day. Always take your medication as prescribed.

Beta-blockers are prescription-only medicines, which means they can only be prescribed by a GP or another suitably qualified healthcare professional.

Here is a list of commonly used beta-blockers (generic name - trade name) in India:

Acebutolol - Sectral
Atenolol - Tenormin
Betaxolol - Kerlone
Bisoprolol - Zebeta, also sold as Ziac
Carteolol - Cartrol
Carvedilol - Coreg
Labetalol - Normodyne, also sold as Trandate
Metoprolol - Lopressor, also sold as Toprol

After a heart attack or acute myocardial infarction (AMI), beta-blockers like metoprolol and carvedilol are commonly prescribed. However, carvedilol may offer added benefits to certain patients due to its additional pharmacological properties. Specifically, for patients with a depressed left ventricular ejection fraction (LVEF) of 40% or lower, carvedilol was associated with improved survival when compared to metoprolol.

LVEF is an indicator of how much blood the heart chamber pumps out with each heartbeat.

No significant differences were observed in survival rates for patients with an LVEF greater than 40%. Nonetheless, it is important to conduct further prospective trials to validate these findings.

Some common side effects of beta-blockers include:

Fatigue
Cold hands or feet
Weight gain
Bradycardia (slower than normal heart rate)
Hypotension (low blood pressure)
Dizziness or lightheadedness
Depression
Shortness of breath or trouble breathing

However, recent studies have raised concerns about the long-term benefits of beta-blockers for these patients.

A study published in the journal Heart analyzed data from over 179,000 patients who had survived a heart attack and were treated with different medications. The researchers found that beta-blockers did not lower the mortality rate or the rate of recurrent heart attacks after one year, indicating that they may not reduce the risk of further heart attacks or death in people who do not have heart failure.

Similarly, another study published in the international journal BMJ Open reviewed 16 randomized trials involving more than 20,000 patients with high blood pressure. The researchers found that beta blockers did not reduce the risk of heart attack or stroke compared to other blood pressure-lowering drugs, suggesting that beta blockers may not be as effective as previously thought in preventing heart attacks.

These findings challenge current guidelines that recommend beta blockers as a first-line treatment for patients with high blood pressure or previous heart attack. The researchers suggest that beta blockers may still be useful for some patients, such as those with heart failure or angina, but they should not be routinely prescribed for everyone.

According to the data collected in real-time, long-term usage of beta blockers didn't appear to result in better cardiovascular outcomes over an average monitoring period of 4.5 years. Out of the individuals on beta blockers, 19% (6475) experienced adverse outcomes such as death from any cause, another heart attack, unscheduled revascularization, or hospitalization due to heart failure. In comparison, 22% (2028) of those who didn't take beta blockers had similar outcomes.

The researchers noted that this is an observational study, meaning it cannot establish causality. Although this study is the largest of its kind so far, there are certain limitations to the findings that should be taken into account. For instance, patients weren't randomly assigned to treatment, the study only included specific cardiovascular outcomes, and there was no information on how consistently patients took their medications or how their quality of life was impacted.

If you are taking beta blockers for your heart condition, it is important not to stop them without consulting your doctor. Your doctor can help you determine if beta blockers are still appropriate for you, or if you need to switch to another medication. Beta blockers can have side effects, including fatigue, cold hands and feet, weight gain, and depression. You should also regularly monitor your blood pressure and adopt a healthy lifestyle to reduce your risk of heart problems.

Tuesday, May 2, 2023

The Brain on the Brink: Understanding the Neuro-Science of the Dying Process

Death is an inevitable part of the human experience. While it is a topic that is often avoided and considered taboo, understanding the processes that occur during the dying process can provide insight into what happens to us in our final moments. The last moments of life have long been a subject of intense scientific study, with researchers exploring the mechanisms and neuro-signatures that occur during the dying process. Recent studies have revealed that the brain may undergo a surge of activity around the time of death, similar to what occurs during dreaming and meditation. In this article, we will explore the latest findings on what happens to the brain and body during the final moments of life, and what it means for our understanding of the dying process.

Recent studies suggest that the brain may undergo a surge of activity around the time of death, similar to what occurs during dreaming and meditation.

According to research published in the Proceedings of the National Academy of Sciences, scientists from the University of Michigan analyzed the electroencephalogram (EEG) and electrocardiogram (ECG) signals in four dying patients before and after the withdrawal of ventilatory support. The four patients were in a state of coma. The researchers discovered rhythmic brain wave patterns around the time of death that are similar to those occurring during dreaming, memory recall, and meditation.

Another study published in Frontiers in Neuroscience found that the dying brain undergoes a surge of activity that is similar to that seen while dreaming and in seizure patients during hallucinations and ‘out of body’ experiences. The study focused on investigating what happened in the 30 seconds before and after the heart stopped beating, measuring 900 seconds of brain activity around the time of death.

The surge of gamma waves observed in previous animal studies is similar to what was observed in the dying patients. Potential neuro-signatures of consciousness were also observed in unresponsive patients at the time of death, according to an article in The Guardian.

However, it is important to note that death marks the moment when the physical body stops working to survive. The heart stops beating, the brain stops, and other vital organs such as the kidneys and liver stop as well. The body immediately begins to relax, releasing any strain on the bowel and bladder, resulting in the loss of control over them. As a result, most people will pass urine and feces at the time of death.

Thanatology, the scientific study of death and the losses that accompany it, investigates the mechanisms and forensic aspects of death as well as the psychological and social aspects related to it. Understanding the processes that occur during the dying process can help us better understand death and the experiences of those who are dying.

In conclusion, recent studies suggest that the brain may undergo a surge of activity around the time of death, similar to what occurs during dreaming and meditation. The findings provide insight into the mechanisms that occur during the dying process and contribute to our understanding of death and the experiences of those who are dying.

Monday, May 1, 2023

Rising Concerns: The Dark Side of Artificial Intelligence and Its Potential to Harm Society

No wonder that with the advent of various chatbots, such as ChatGPT3, ChatGPT4, Bard, etc., which have human-like capabilities to respond to any queries on various topics of interest, Artificial Intelligence (AI) has caught the imagination of the global public, just as search engines and the internet did many decades ago. AI is undoubtedly an exciting field to explore, and there are great expectations for further developments that can make our lives easier, better, and more efficient. However, as AI technology continues to advance at an unprecedented pace, there are growing concerns about the potential risks and dangers it poses to society and humanity as a whole

Indeed, AI is an exciting field to explore, and there are high expectations for further development in this regard, which we all hope will make our lives easier, better, and more efficient. With AI technology advancing rapidly, there is a growing concern about the potential risks and dangers it may pose to society and humanity as a whole.

The “Godfather of AI,” Geoffrey Hinton, recently made headlines by quitting his role at Google and speaking out about the “dangers” of artificial intelligence. Hinton, who played a key role in developing the intellectual foundation for AI systems, is now among a growing number of experts warning about the risks of AI, saying that these risks are coming sooner than expected.

In a previous interview with the BBC, Hinton expressed concern about the possibility of AI wiping out humanity, calling the chances “not inconceivable.” He also expressed immediate worries about the internet being flooded with false photos, videos, and text, to the point where the average person will “not be able to know what is true anymore.

Hinton regrets his life’s work and admits that he thought he had more time to talk about the potential threat of AI. He left Google so he could speak freely about the risks of AI, not to criticize the tech giant specifically.

Hinton’s concerns about AI are not unfounded. Over 1,000 technology leaders and researchers have signed an open letter calling for a six-month suspension of AI development, citing the “profound risks to society and humanity” that AI poses. Despite these concerns, Google has created its own chatbot, Bard, which has raised concerns about AI-powered chatbots spreading misinformation and potentially displacing jobs.

The risks associated with AI are real and must be taken seriously. From job displacement to social manipulation and bias, the potential negative consequences of AI are significant. As Hinton and others have warned, the time to act is now. We must work together to ensure that AI is developed in a responsible manner that benefits society as a whole.

One of the most pressing concerns regarding AI is the risk of job losses due to AI automation. AI-powered job automation is becoming increasingly prevalent as the technology is adopted, and there are fears that it could lead to widespread unemployment and social unrest.

Another risk associated with AI is social manipulation through AI algorithms. AI can be used to manipulate people's behavior on social media, which could have serious implications for democracy, human rights, and social cohesion.

AI can also be used for social surveillance, which raises concerns about privacy and individual freedoms. AI systems can collect and analyze vast amounts of personal data without the explicit consent of individuals, making it difficult to control or limit their use.

Another major concern regarding AI is biases due to artificial intelligence. AI systems can be biased and discriminatory, perpetuating and amplifying existing social and cultural biases.

AI also has the potential to widen socioeconomic inequality, as the benefits of AI technology may not be distributed equitably across society. This could lead to a further concentration of wealth and power in the hands of a few, exacerbating existing social and economic disparities.

Furthermore, AI can weaken ethics and goodwill, potentially eroding the moral fabric of society. The use of AI for nefarious purposes, such as cyberattacks or social manipulation, could erode trust and cooperation, leading to a breakdown in social cohesion.

Autonomous weapons powered by artificial intelligence are another major concern, as they could be used to wage war and cause significant harm to human life and property. The development of AI-powered weapons raises important questions about the role of technology in warfare and the need for ethical frameworks to govern their use.

There are concerns about financial crises brought about by AI algorithms. The use of AI for high-frequency trading and other financial activities could potentially lead to systemic risks and destabilize global financial markets.

Invasion of personal data: One of the primary concerns regarding AI is the collection and analysis of personal data without explicit consent. This can lead to privacy violations and put individuals at risk.

Risk of cyberattack: Like any technology, AI systems can be vulnerable to cyberattacks. The consequences of such attacks can be severe, especially if the AI system is used in critical infrastructure.

Discrimination and bias: AI systems can perpetuate societal biases and discriminations, leading to unfair and unethical decisions.

Opacity and lack of transparency: AI systems can be opaque and lack transparency, making it difficult to understand how they reach their decisions or why they produce certain outputs.

Accountability of AI-driven decisions: It is difficult to hold AI systems accountable for their decisions, which can lead to a loss of trust in the technology and its applications.

Replacement of jobs: AI-powered job automation is a pressing concern as the technology is adopted. AI systems can automate tasks previously performed by humans, potentially leading to job displacement and socioeconomic inequality.

In conclusion, while AI holds immense promise for improving our lives, we must also be mindful of the potential risks and dangers it poses. It is essential that we take a responsible approach to the development and deployment of AI technology, with a focus on transparency, accountability, and ethical considerations. Only then can we fully realize the potential of AI while minimizing its potential harms.

Google honors late actor Alan Rickman with a special doodle



Google has dedicated its homepage doodle to the late English actor Alan Rickman, who would have turned 77 on April 30, 2023. The doodle features an animated portrait of Rickman, capturing his distinctive facial expression and charisma.

Rickman was a versatile and acclaimed actor, who played memorable roles in films such as “Harry Potter”, “Die Hard”, “Sense and Sensibility”, and “Galaxy Quest”. He also had a distinguished career in theatre, especially with the Royal Shakespeare Company.

The doodle celebrates Rickman’s breakthrough performance as Le Vicomte de Valmont in the Broadway play “Les Liaisons Dangereuses” (Dangerous Liaisons), which premiered on this day in 1987. The play earned him a Tony nomination and paved the way for his film debut as Hans Gruber in “Die Hard” the following year.

Rickman passed away in 2016 after a battle with pancreatic cancer. He is remembered for his iconic roles on-screen, his philanthropy, and his kind and sensitive nature off-screen. He also directed three plays and two films in his lifetime.

Google said in a blog post that the doodle aims to honor Rickman’s legacy and inspire people to explore his work. The doodle is visible in several countries, including the UK, India, Australia, Canada, and the US.

Beware of the Atomic macOS Stealer: A new malware that targets Mac users

Most often than not most Mac users are naive as they are under the false impression that their devices are more secure than the other devices using different operating systems such as the Windows or Linux, unfortunately that may not hold true anymore.

A new malware that has been recently branded as the Atomic macOS Stealer (AMOS) is being sold across Telegram for $1,000 per month, and without the Mac user getting any inkling whatsoever, the said malaware can quitely steal a wide range of sensitive information from the victim’s machine.

As per a report submitted for perusal Cyble Research and Intelligence Labs (CRIL), AMOS is specifically designed to target macOS platforms and can extract autofill information, passwords, wallets, credit card information, files, and more from the victim’s machine. The malware can also target multiple browsers and cryptocurrency wallets, making it a serious threat for Mac users who store or transact with digital currencies.

The malware is being clandestinely sold by a threat actor named Atomic who claims to have over 100 customers and offers a free trial for potential buyers. The threat actor also provides additional services such as a web panel for managing victims, meta mask brute-forcing to steal seed and private keys, a crypto checker, and a dmg installer, after which the logs are shared via Telegram.

The malware is written in Python and uses PyInstaller to create a standalone executable file. The malware uses a fake system dialog box to trick users into entering their system password, which allows it to access the keychain and other protected data. The malware then scans for sensitive information, which it steals with the system password if necessary, and sends it to a remote server.

The malware is distributed via phishing emails or malicious websites that trick users into downloading and running it. The malware is one of the first to target Apple Silicon Macs, which have a different architecture than Intel-based Macs. The malware can also bypass macOS Gatekeeper and encrypt the stolen data before sending it to the attacker.

The malware is part of a growing trend of cryptominers targeting macOS platforms, which accounted for almost 40% of all malware detections on Macs in 2023. Cryptominers are malicious programs that use the victim’s computing resources to mine cryptocurrencies without their consent or knowledge. Cryptominers can slow down the system performance, increase the power consumption, and cause overheating issues.

Mac users are advised to update their systems regularly, avoid clicking on suspicious links or attachments, and use reputable antivirus software to protect themselves from the malware. Mac users should also use strong passwords and enable multi-factor authentication wherever possible. They should also be wary of enabling any permissions or entering their system password for unknown applications.

AMOS is a new malware that poses a serious risk for Mac users who value their privacy and security. Mac users should be aware of this threat and take preventive measures to avoid becoming victims of this malicious software.

What actually is AMOS and how does it work?

AMOS is a new information-stealing malware that targets macOS platforms. It is sold on Telegram by a threat actor named Atomic who offers various services and features to his customers. AMOS can steal different types of information from the victim’s machine, such as:

Keychain passwords: These are passwords that are stored in the macOS keychain, which is a secure storage for passwords and other sensitive data. AMOS can access the keychain by using the system password that it obtains from the user through a fake dialog box.

System information: This includes information such as the device model, serial number, OS version, CPU type, RAM size, disk space, network interfaces, installed applications, etc. AMOS can use this information to identify the victim’s machine and its capabilities.

Files: AMOS can scan the desktop and documents folders for files that may contain valuable information. It can also search for specific file extensions such as .pdf, .docx, .xlsx, .pptx, etc.

Browser data: AMOS can target multiple browsers such as Chrome, Firefox, Brave, Edge, Vivaldi, Yandex and Opera. It can extract autofill information, passwords, cookies, credit card information and history from these browsers. It can also steal cryptocurrency wallets from browser extensions such as MetaMask.

Cryptocurrency wallets: AMOS can also target standalone cryptocurrency wallets such as Electrum, Binance, Exodus,Okay, I will write more till it is at least 1000 words. Here is a possible continuation of the article:

Atomic and Coinomi: It can extract seed phrases, private keys and wallet addresses from these wallets.

Other data: AMOS can also steal other types of data such as screenshots, clipboard content, camera snapshots, microphone recordings, etc. AMOS works by creating a .dmg file that contains the malware executable and a fake icon and name to lure the user into installing it.

The .dmg file can be sent to the user via email or downloaded from a malicious website. Once the user opens the .dmg file, they will see a fake system dialog box asking for their system password. If the user enters their password, the malware will be installed and run in the background.

The malware will then scan the victim’s machine for sensitive information and send it to a remote server controlled by the attacker. The malware will also encrypt the stolen data before sending it to prevent detection and analysis. The attacker can access the stolen data through a web panel or a Telegram channel.

How to protect yourself from AMOS and other malware?

AMOS is a new and sophisticated malware that can steal a lot of sensitive information from Mac users. However, there are some steps that Mac users can take to protect themselves from this and other malware. These include:

Update your system regularly: Apple releases security updates for macOS that can fix vulnerabilities and prevent malware infections. You should always keep your system up to date with the latest patches and updates.

Avoid clicking on suspicious links or attachments: Phishing emails and malicious websites are common ways of distributing malware. You should never click on links or attachments that you don’t trust or that look suspicious. You should also check the sender’s address and the URL of the website before clicking on anything.

Use reputable antivirus software: Antivirus software can detect and remove malware from your system. You should use a reputable antivirus software that has good ratings and reviews. You should also update your antivirus software regularly and scan your system frequently.

Use strong passwords and enable multi-factor authentication: Passwords are often the first line of defense against hackers and malware. You should use strong passwords that are long, complex and unique for each account. You should also enable multi-factor authentication wherever possible, which adds an extra layer of security by requiring a code or a device to log in.

Be wary of enabling any permissions or entering your system password for unknown applications: Malware often needs permissions or passwords to access sensitive data or run malicious code. You should be careful about enabling any permissions or entering your system password for applications that you don’t know or trust. You should also check the source and legitimacy of the application before installing it.

Conclusion

AMOS is a new and sophisticated malware that can steal a wide range of sensitive information from Mac users. It is sold on Telegram for $1,000 per month and offers various services and features to its customers. It can target multiple browsers and cryptocurrency wallets, as well as keychain passwords, system information, files and other data. It can also bypass macOS Gatekeeper and encrypt the stolen data before sending it to the attacker.

Mac users are advised to update their systems regularly, avoid clicking on suspicious links or attachments, use reputable antivirus software, use strong passwords and enable multi-factor authentication, and be wary of enabling any permissions or entering their system password for unknown applications. Mac users should be aware of this threat and take preventive measures to avoid becoming victims of this malicious software.

Beyond the Womb: Exploring the Brave New World of Artificial Wombs

 As I flipped through the morning newspaper, a particular report grabbed my attention, uncovering a captivating yet intricate frontier in re...